The sequence and structure of a new serum amyloid A gene.

نویسندگان

  • R S Stearman
  • C A Lowell
  • C G Peltzman
  • J F Morrow
چکیده

The acute phase response is characterized by changes in the serum concentrations of many proteins. A 1000-fold increase in the concentration of serum amyloid A (SAA) protein occurs within 24 hours of LPS injection in the mouse. We have isolated a cDNA clone and its corresponding genomic phage for a third, previously unreported SAA protein. The sequence of the cDNA, the gene's exons and neighboring DNA are presented along with the mapping evidence supporting the gene structure.

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عنوان ژورنال:
  • Nucleic acids research

دوره 14 2  شماره 

صفحات  -

تاریخ انتشار 1986